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双导丝聚力球囊预扩张对小血管支架置入术的影响
作者:张琳琳 周玉杰 赵迎新 郭永和 杨清 闫振娴 梁静 杨丽霞 王建龙 
单位:100029 首都医科大学附属北京安贞医院十二病房 
关键词:小血管病变 血管成形术 气囊 冠状动脉 双导丝聚力球囊 
分类号:R 541
出版年,卷(期):页码:2012,7(7):807-810
摘要:

【摘要】 目的 探讨双导丝聚力球囊预扩张较普通球囊能否降低小血管支架置入术围术期并发症及改善支架置入术远期预后。方法 连续入选冠状动脉造影显示小血管病变(参考血管直径2.75 mm)需行冠状动脉介入治疗的患者300例,完全随机分成研究组和对照组,每组150例。研究组:双导丝聚力球囊预扩张后置入支架;对照组:普通球囊预扩张后置入支架。观察冠状动脉介入治疗即刻成功率、血管并发症发生率。912个月复查冠状动脉造影,观察靶病变再狭窄发生率,12个月内不良心血管事件(MACE)发生率。结果 研究组与对照组冠状动脉介入治疗手术成功率分别为98.7%(148)94.7%(142),手术并发症发生率分别为1.3%(2)5.3%(8),组间差异有统计学意义(P0.05)912个月复查冠状动脉造影,研究组和对照组的MACE发生率分别为3.4%(5/148)7.0%(10/142),组间差异无统计学意义(P0.05)结论 双导丝聚力球囊较普通球囊扩张可降低小血管支架置入术围术期手术并发症,并具有改善支架置入术远期预后的趋势。

Abstract】 Objective To assess the effect of dual-wire focused force balloon predilation followed by drug-eluting stent placement for lesions of small coronary arteries. Methods Through coronary angiography 300 consecutive patients with unstable angina(reference vessel 2.75 mm in diameter) were randomly assigned to experimental group (dual-wire focused force balloon predilation group) and control group (balloon predilation group). Restenosis at 9-12 month were followed up through angiography. Clinic improvement and major adverse cardiac event (MACE) at 1 year were assessed. Results Procedural success was achieved in 98.7%(148/150) of patients assigned to experimental group and in 94.7%(142/150) of patients assigned to control group (P0.05). Vessels complications in these two groups were 1.3%(2/150) and 5.3%(8/150) respectively (P0.05). Less patients in experimental group experienced major adverse cardiac event [5/148(3.4%) vs 10/142(7.0%) P0.05]. There was no statistical difference between these two groups regarding restenosis and MACE but the procedural success rate and vessel complications were different. Conclusion Dual-wire focused force balloon predilation reduced the incidence of perioperatine complications and provided tendency of improving outcomes followed by drug-eluting stent placement in small vessels.

基金项目:
作者简介:
作者单位:100029 首都医科大学附属北京安贞医院十二病房 通信作者:周玉杰,Email:azzyj12@163.com
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