2022 年第 5 期 第 17 卷

冠状动脉功能学评估指标定量血流分数的临床应用及进展

Clinical application and progress of coronary artery function evaluated index quantitative flow ratio

作者：王衍刘雨薇王一彪曾玉杰

英文作者：Wang Yan Liu Yuwei Wang Yibiao Zeng Yujie

单位：首都医科大学附属北京安贞医院冠心病中心急诊冠脉病区，北京100029

英文单位：Department of Acute Coronary Syndrome Ward Center for Coronary Artery Disease Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

关键词：冠心病（冠状动脉粥样硬化性心脏病）；定量血流分数；血流储备分数

英文关键词：Coronaryatheroscleroticheartdisease;Quantitativeflowratio;Fractionalflowreserve

• 摘要：

• 冠状动脉的功能学评估在指导冠心病（冠状动脉粥样硬化性心脏病）患者的血运重建中具有关键作用，定量血流分数（QFR）近年来在国内外备受关注。与指南推荐的“金标准”血流储备分数相比，QFR评估冠状动脉狭窄所致心肌缺血的准确性及可行性已在大量研究中得到证实。此外，临床试验也成功将QFR的临床应用推向了新的高潮。基于国内外研究现状，本文就QFR的测量、诊断性能以及当前临床应用及预后评估进行综述。

• The functional assessment of coronary arteries plays a key role in guiding revascularization of patients with coronary atherosclerotic heart disease. Quantitative flow ratio (QFR) has attracted much attention both at home and abroad in recent years. Compared with the "gold standard" of fractional flow reserve recommended by the guidelines, the accuracy and feasibility of QFR in assessing myocardial ischemia caused by coronary stenosis has been confirmed in a large number of studies. In addition, clinical trials have successfully pushed the clinical application of QFR to a new climax. Based on the current research status at home and abroad, this article reviews the measurement, diagnostic performance, current clinical applications and prognostic evaluation of QFR.