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英文作者:Liang Ling1 Wang Hengyue1 Zhou Ping2 Xu Jing2 Liu Xiaodong3 Wang Yingxia3
单位:1安徽医科大学第一附属医院北区(安徽省公共卫生临床中心)儿科,合肥230012;2安徽省青阳县中医院儿科,青阳247100;3安徽省黄山市华泽中西医结合医院儿科,黄山245000
英文单位:1Department of Pediatrics The First Affiliated Hospital of Anhui Medical University North District (Anhui Public Health Clinical Center) Hefei 230012 China; 2Department of Pediatrics Qingyang County Hospital of Traditional Chinese Medicine Anhui Province Qingyang 247100 China; 3Department of Pediatrics Huangshan Huaze Hospital of Integrated Traditional Chinese and Western Medicine Anhui Province Huangshan 245000 China
英文关键词:Shortstaturechildren;Springpediatricgrowthplaster;Spleenandkidneydeficiencysyndrome
目的 观察春季儿童生长贴联合生活调摄治疗身材偏矮儿童的临床效果。方法 采用随机对照试验的方法 ,选取2023年1—3月和2024年1—3月安徽医科大学第一附属医院北区、安徽省青阳县中医院及安徽省黄山市华泽中西医结合医院接诊的440例身材偏矮儿童作为研究对象,按照随机数字表法分为对照组及治疗组,每组220例。对照组予生活调摄治疗,包括但不限于运动、睡眠、营养干预;治疗组在此基础上加用春季儿童生长贴治疗。比较2组的治疗总有效率、身高增长值、月生长速率以及中医证候评分、不良反应等情况。结果 治疗组总有效率显著高于对照组[62.7%(138/220)比47.2%(104/220)](P<0.001),疗效明显好于对照组(P=0.004)。治疗组在身高增长值及月生长速率方面明显高于对照组[(1.34±0.71)cm比(0.82±0.56)cm、(0.67±0.36)cm/月比(0.41±0.28)cm/月],差异均有统计学意义(均P<0.001)。治疗后,治疗组中医证候评分明显低于对照组(P<0.001)。治疗组有10例患儿在治疗初期出现皮肤发红伴瘙痒,经外用地奈德乳膏后很快缓解,不影响下一次的贴敷。对照组未发生不良反应。结论 春季儿童生长贴联合生活调摄治疗身材偏矮儿童脾肾亏虚证,疗效确切,显著改善中医证候,提高身高增长值及月生长速率。
Objective To observe the clinical efficacy of spring pediatric growth plaster combined with lifestyle regulation in the treatment of short stature children. Methods A randomized controlled trial was conducted. A total of 440 children with short stature admitted to The First Affiliated Hospital of Anhui Medical University North District, Qingyang County Hospital of Traditional Chinese Medicine, Anhui Province and Huangshan Huaze Hospital of Integrated Traditional Chinese and Western Medicine, Anhui Province from January to March 2023 and January to March 2024 were enrolled. The subjects were divided into control group and treatment group by random number table method, with 220 cases in each group. The control group received lifestyle regulation including exercise, sleep and nutritional intervention; on this basis, the treatment group was additionally treated with spring pediatric growth plaster. The total effective rate, height growth, monthly growth rate, traditional Chinese medicine syndrome score and adverse reactions were compared between the two groups. Results The total effective rate of the treatment group was significantly higher than that of the control group [62.7%(138/220) vs 47.2%(104/220)](P<0.001), with obviously better curative effect (P=0.004). The height growth and monthly growth rate in the treatment group were significantly higher than those in the control group [(1.34±0.71)cm vs (0.82±0.56)cm, (0.67±0.36)cm/month vs (0.41±0.28)cm/month](both P<0.001). After treatment, the traditional Chinese medicine syndrome score of the treatment group was markedly lower than that of the control group (P<0.001). In the treatment group, 10 children presented skin redness accompanied by pruritus at the initial stage of treatment, which was quickly relieved by external application of desonide cream without affecting subsequent application. No adverse reactions occurred in the control group. Conclusion Spring pediatric growth plaster combined with lifestyle regulation has definite curative effect on short stature children with spleen and kidney deficiency syndrome, which can significantly improve traditional Chinese medicine symptoms and increase height growth and monthly growth rate.
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