2026 年第 8 期 第 21 卷

维持性血液透析患者不宁腿综合征的研究进展

Research progress of restless legs syndrome in maintenance hemodialysis patients

作者：王明启罗琰琨

英文作者：Wang Mingqi Luo Yankun

单位：山西医科大学附属山西省人民医院肾内科，太原030012

英文单位：Department of Nephrology Shanxi Provincial People′s Hospital Shanxi Medical University Taiyuan 030012 China

关键词：不宁腿综合征；血液透析；影响因素；发病机制；干预措施

英文关键词：Restlesslegssyndrome;Hemodialysis;Influencingfactors;Pathogenesis;Interventionmeasures

• 摘要：

• 不宁腿综合征（RLS）在维持性血液透析（MHD）患者中具有高患病率，可显著降低睡眠质量并增加心血管风险。本文基于近年来国内外研究，综述RLS在MHD患者中的流行病学特征、主要机制、临床影响、干预证据及未来研究方向，旨在为临床管理和研究设计提供参考。

• Restless legs syndrome (RLS) has a high prevalence in maintenance hemodialysis (MHD) patients, which can significantly reduce sleep quality and increase cardiovascular risk. Based on recent domestic and international studies, this article reviews the epidemiological characteristics, main mechanisms, clinical impacts, intervention evidence and future research directions of RLS in MHD patients, aiming to provide references for clinical management and research design.